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Fully-Automated Quantification of Regional Brain Volumes for Improved Detection of Focal Atrophy in Alzheimers Disease AJNR 30:578-580, Brewer, J.B.,et al, 2009 See this aricle in Pubmed Article Abstract Volumetric analysis of structural MR images of the brain may provide quantitative evidence of neurodegeneration and help identify patients at risk for rapid clinical deterioration. This note describes tests of a fully automated MR imaging postprocessing system for volumetric analysis of structures (such as the hippocampus) known to be affected in early Alzheimer disease (AD). The system yielded results that correlated highly with independent computer-aided manual segmentation and were sensitive to the anatomic atrophy characteristic of mild AD.

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(click to filter results - removes previous filter) Alzheimer's disease biologic markers brain atrophy brain volume dementia hippocampal atrophy hippocampus lobar atrophy MRI MRI,abnormal MRI,morphometyry MRI,volumetry temporal lobe temporal lobe,atrophy ventricular enlargement

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